Antigen: human and rat amino acids 130-149; The sequence is 95% homologous to 5-LO from mouse and hamster Host: rabbit Cross Reactivity: (+) human, rat, mouse, hamster, and porcine 5-LO; (−) 12-LO and 15-LO Application(s): WB 5-LO catalyzes the formation of 5(S)-HpETE from arachidonic acid as well as its subsequent conversion to LTA4.
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