Albumin gene is mapped to human chromosome 4q13.3. It is synthesized as a preproalbumin with 609 amino acids in the liver. The mature albumin comprising 585 residues, is generated by the cleavage of signal peptide. Albumin is the major circulating protein in serum. It comprises three domains (I, II and III), each of which is subdivided into two subdomains A and B. A total of six ligand binding site is associated with albumin. Domain IIA and IIIA harbor small heterocyclic or aromatic compounds binding site. Long-chain fatty acid binding sites is present in IB and IIIB domains.Application:Albumin, glycated human has been used:as a component of serum-free medium for retinal microglia activationto stimulate immortalised proximal tubule epithelial (HK-2) cells for fibronectin productionas medium supplement in human retinal microvascular endothelial cells (HRMECs) cultures to test its effect on family with sequence similarity 18, member B (FAM18B) expressionNaturally occurring glycated albumin is a sensitive indicator of glycemic control by diabetic patients.
Specification: lyophilized powder
- UPC:
- 51172818
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A754956-25mg
- Product Size:
- 25mg
