Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR , and Anagyrine can directly, without metabolism, desensitize nAChR .In VitroAnagyrine acts as a partial agonist in both cell lines with EC 50 values of 4.2 and 231 μM in SH-SY5Y and TE-671 cells, respectively. Anagyrine is a desensitizer of nAChR with DC 50 values of 6.9 and 139 μM in SH-SY5Y and TE-671 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Oil. Specification: 0.97 Molecular Formula: C15H20N2O Molecular Weight: 244.33 PubChem CID: 442938 Isomeric SMILES: C1CCN2C[C@@H]3C[C@@H]([C@H]2C1)CN4C3=CC=CC4=O
- UPC:
- 51142314
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A647058-5mg
- CAS:
- 486-89-5
- Product Size:
- 5mg
