Anti-RAB35 Antibody (C15-1317-568)

General description

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Specificity

This antibody recognizes RAB35 at the C-terminus.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.

This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Target description

~19 kDa observed. The calculated molecular weight is 23 kDa

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: rat, human, horse. species reactivity (predicted by homology): canine (based on 100% sequence homology), equine (based on 100% sequence homology). technique(s): immunohistochemistry: suitable (paraffin), western blot: suitable. NCBI accession no.: NP_006852. UniProt accession no.: Q15286. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... RAB35(11021). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.