General description
Special AT-rich sequence-binding protein 2 (SATB2) contains 2 CUT DNA-binding domains and one homeobox DNA binding domain belonging to the CUT homeobox family. SATB2 binds to DNA at the nuclear matri or scaffold-associated regions. SATB2 is highly expressed in adult brain, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord. Mutations in SATB2 have been associated with cleft palate.
Specificity
This antibody recognizes the N-terminus of SATB2.
Immunogen
Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of human SATB2.
Application
Detect Special AT-rich sequence-binding protein 2 using this rabbit polyclonal antibody, Anti-SATB2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SATB2 in human brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SATB2 in human brain cells.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Quality
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected SATB2 in 15 µg of mouse brain tissue lysate.
Target description
~90 kDa observed
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Mouse brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
biological source: rabbit. Quality Level: 100. antibody form: affinity isolated antibody. antibody product type: primary antibodies. clone: polyclonal. purified by: affinity chromatography. species reactivity: human, mouse. technique(s): immunofluorescence: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable. UniProt accession no.: Q9UPW6. shipped in: wet ice. target post-translational modification: unmodified. Gene Information: human ... SATB2(23314). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51202416
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- ABE600