AZD-7762 (C005B-313478)

Catalog No.: C005B-313478
Mfr. No.: SML0350-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $307.43

List Price: $341.59

Application AZD-7762 hydrochloride has been used: as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) repair in breast cancer cell lines as a CHK1 inhibitor to serve as a

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Description
Specifications

Application

AZD-7762 hydrochloride has been used:

as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) repair in breast cancer cell lines
as a CHK1 inhibitor to serve as a positive control for replication stress in the assessment of fork restart events
as a CHK1/2 inhibitor to study its effects on DNA lesions during mice zygote development

Biochem/physiol Actions

AZD-7762 is a potent, ATP-competitive inhibitor of Chk1 and Chk2 that enhanced cytotoxicity DNA-damaging agents.

UPC:: 51171829
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0350-5MG
CAS:: 1246094-78-9

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