InformationDanicopan (ACH-4471) Danicopan (ACH-4471, ACH-0144471, ACH-CFDIS, ALXN 2040) is a potent, selective and orally active inhibitor of factor D with Kd of 0.54 nM for human Factor D. Danicopan inhibits alternative pathway of complement (APC) activity, and has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).Targetsalternative pathway of complement (APC) ; human Factor D (Cell-free assay) ; 0.54 nM(Kd). Specification: 0.99 Molecular Formula: C26H23BrFN7O3 Molecular Weight: 580.41 PubChem CID: 118323590 Isomeric SMILES: CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4C[C@@H](C[C@H]4C(=O)NC5=NC(=CC=C5)Br)F
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D412556-25mg
- CAS:
- 1903768-17-1
- Product Size:
- 25mg
