Laboratory

A natural indole alkaloid with demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions an AhR antagonist (Ki = 28 nM), activator of TRPV1 (EC₅₀ = 45 nM), and inhibitor of signaling through NF-&kappaB.

A natural indole alkaloid with demonstrated beneficial effects in cancer, obesity, inflammation, and many other conditions an AhR antagonist (Ki = 28 nM), activator of TRPV1 (EC₅₀ = 45 nM), and inhibitor of signaling through NF-&kappaB.

Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 mouse leukemia cells and pesticidal activities.

Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 mouse leukemia cells and pesticidal activities.

Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 mouse leukemia cells and pesticidal activities.

Formula: C17H17ClO6 Formula weight: 352.77 Purity: 97% CAS Number: 126-07-8 Harmonized Tariff Code:  2941.

Formula: C17H17ClO6 Formula weight: 352.77 Purity: 97% CAS Number: 126-07-8 Harmonized Tariff Code:  2941.

Formula: C17H17ClO6 Formula weight: 352.77 Purity: 97% CAS Number: 126-07-8 Harmonized Tariff Code:  2941.

Formula: C9H9NO2 Formula weight: 163.18 Purity: 95% CAS Number: 78348-24-0 Harmonized Tariff Code:  2933.

Formula: C9H9NO2 Formula weight: 163.18 Purity: 95% CAS Number: 78348-24-0 Harmonized Tariff Code:  2933.

CAS No.: 24808-52-4

Displaces BET proteins from chromatin by competitively binding to the acetyl-lysine recognition pocket of BET bromodomains binds BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively.