Biologically Active Small Molecules

An immunomodulatory and antiproliferative compound that interacts directly with the protein CRBN (IC₅₀ = 8.5 nM), a ubiquitously-expressed E3 ligase, and DDB1 complexes.

A dithiol used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality.

A dithiol used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality.

A dithiol used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality.

An internal standard for the quantification of verapamil (hydrochloride) by GC- or LC-MS.

An internal standard for the quantification of verapamil (hydrochloride) by GC- or LC-MS.

An internal standard for the quantification of verapamil (hydrochloride) by GC- or LC-MS.

A racemic mixture of two optically active isomers, the R and S forms has a half-life of 36-42 hours in circulation, bound to plasma proteins, and accumulates in the liver, where the two isomers are metabolized by different pathways also used as a

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 &microM) demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 &microM) demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 &microM) demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 &microM) demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently