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Biologically Active Small Molecules

  
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    18528-5

    (R)-Gyramide A (hydrochloride)-5 mg

    Price: $205.44
    List Price: $228.27
    A bacterial DNA gyrase inhibitor that disrupts supercoiling activity (IC<sub>50</sub> = 3.3 &microM) demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs range from 10-80 &microM).
    SKU18528-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0325-533
    Pack Size 1 EA
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    Price: $205.44
    List Price: $228.27
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    16794-100

    (R)-Ibuprofen-100 mg

    Price: $170.10
    List Price: $189.00
    An enantiomer of ibuprofen that does not inhibit COX inhibits NF-&kappaB activation (IC<sub>50</sub> = 121.8 &microM) in response to T-cell stimulation blocks superoxide formation, &beta-glucuronidase release, and LTB4 generation by stimulated
    SKU16794-100
    MFR. NameCayman Chemical Company
    Catalog No. C08-0324-436
    Pack Size 1 EA
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    Price: $170.10
    List Price: $189.00
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    16794-250

    (R)-Ibuprofen-250 mg

    Price: $335.15
    List Price: $372.38
    An enantiomer of ibuprofen that does not inhibit COX inhibits NF-&kappaB activation (IC<sub>50</sub> = 121.8 &microM) in response to T-cell stimulation blocks superoxide formation, &beta-glucuronidase release, and LTB4 generation by stimulated
    SKU16794-250
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-057
    Pack Size 1 EA
    Price:
    Price: $335.15
    List Price: $372.38
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    16794-500

    (R)-Ibuprofen-500 mg

    Price: $588.50
    List Price: $653.89
    An enantiomer of ibuprofen that does not inhibit COX inhibits NF-&kappaB activation (IC<sub>50</sub> = 121.8 &microM) in response to T-cell stimulation blocks superoxide formation, &beta-glucuronidase release, and LTB4 generation by stimulated
    SKU16794-500
    MFR. NameCayman Chemical Company
    Catalog No. C08-0334-310
    Pack Size 1 EA
    Price:
    Price: $588.50
    List Price: $653.89
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    18235-10

    (R)-Lansoprazole-10 mg

    Price: $77.11
    List Price: $85.68
    A pure enantiomer of lansoprazole that inhibits acid formation in isolated canine parietal cells with an IC<sub>50</sub> value of 59 nM and inhibits the H+/K+-ATPase with an IC<sub>50</sub> value of 4.2 &microM.
    SKU18235-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0319-192
    Pack Size 1 EA
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    Price: $77.11
    List Price: $85.68
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    18235-100

    (R)-Lansoprazole-100 mg

    Price: $376.81
    List Price: $418.68
    A pure enantiomer of lansoprazole that inhibits acid formation in isolated canine parietal cells with an IC<sub>50</sub> value of 59 nM and inhibits the H+/K+-ATPase with an IC<sub>50</sub> value of 4.2 &microM.
    SKU18235-100
    MFR. NameCayman Chemical Company
    Catalog No. C08-0330-890
    Pack Size 1 EA
    Price:
    Price: $376.81
    List Price: $418.68
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    18235-50

    (R)-Lansoprazole-50 mg

    Price: $240.79
    List Price: $267.54
    A pure enantiomer of lansoprazole that inhibits acid formation in isolated canine parietal cells with an IC<sub>50</sub> value of 59 nM and inhibits the H+/K+-ATPase with an IC<sub>50</sub> value of 4.2 &microM.
    SKU18235-50
    MFR. NameCayman Chemical Company
    Catalog No. C08-0326-420
    Pack Size 1 EA
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    Price: $240.79
    List Price: $267.54
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  • (r)-lisofylline-1 mg
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    13616-1

    (R)-Lisofylline-1 mg

    Price: $171.09
    List Price: $190.10
    A potent inhibitor of the generation of phosphatidic acid (IC<sub>50</sub> = 0.6 &microM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock suppresses the production of the
    SKU13616-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0323-703
    Pack Size 1 EA
    Price:
    Price: $171.09
    List Price: $190.10
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  • (r)-lisofylline-10 mg
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    13616-10

    (R)-Lisofylline-10 mg

    Price: $979.05
    List Price: $1,087.84
    A potent inhibitor of the generation of phosphatidic acid (IC<sub>50</sub> = 0.6 &microM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock suppresses the production of the
    SKU13616-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0337-405
    Pack Size 1 EA
    Price:
    Price: $979.05
    List Price: $1,087.84
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  • (r)-lisofylline-5 mg
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    13616-5

    (R)-Lisofylline-5 mg

    Price: $553.15
    List Price: $614.61
    A potent inhibitor of the generation of phosphatidic acid (IC<sub>50</sub> = 0.6 &microM) from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock suppresses the production of the
    SKU13616-5
    MFR. NameCayman Chemical Company
    Catalog No. C08-0333-699
    Pack Size 1 EA
    Price:
    Price: $553.15
    List Price: $614.61
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    13697-1

    (R)-MG132-1 mg

    Price: $106.02
    List Price: $117.80
    A potent, reversible, and cell permeable proteasome inhibitor a more effective inhibitor of chymotrypsin-like, trypsin-like, and peptidylglutamyl peptide hydrolyzing proteasome activities compared to (S)-MG132 (IC<sub>50</sub>s = 0.22 versus 0.
    SKU13697-1
    MFR. NameCayman Chemical Company
    Catalog No. C08-0321-037
    Pack Size 1 EA
    Price:
    Price: $106.02
    List Price: $117.80
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    13697-10

    (R)-MG132-10 mg

    Price: $602.63
    List Price: $669.58
    A potent, reversible, and cell permeable proteasome inhibitor a more effective inhibitor of chymotrypsin-like, trypsin-like, and peptidylglutamyl peptide hydrolyzing proteasome activities compared to (S)-MG132 (IC<sub>50</sub>s = 0.22 versus 0.
    SKU13697-10
    MFR. NameCayman Chemical Company
    Catalog No. C08-0334-512
    Pack Size 1 EA
    Price:
    Price: $602.63
    List Price: $669.58
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