Synthetic organic

BI-4142 is a potent, highly selective and orally active HER2 inhibitor with an IC50 of 5 nM.

BI-4142 is a potent, highly selective and orally active HER2 inhibitor with an IC50 of 5 nM.

BI-6901.

BI-6901.

InformationBI-7273 BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay.TargetsBRD9 (Cell-free assay): BRD7 (Cell-free assay) 19 nM: 117 nM.

InformationBI-7273 BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay.TargetsBRD9 (Cell-free assay): BRD7 (Cell-free assay) 19 nM: 117 nM.

InformationBI-7273 BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay.TargetsBRD9 (Cell-free assay): BRD7 (Cell-free assay) 19 nM: 117 nM.

InformationBI-7273 BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay.TargetsBRD9 (Cell-free assay): BRD7 (Cell-free assay) 19 nM: 117 nM.

BI-7273.

BI-7273.

BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold

BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold