Molecular Biology

p27 is an important regulator of cell cycle progression, involved in G1 arrest. It is a potent inhibitor of cyclin E1- and cyclin A-CDK2 complexes and a positive regulator of cyclin D-dependent kinases such as CDK4.

p27 is an important regulator of cell cycle progression, involved in G1 arrest. It is a potent inhibitor of cyclin E1- and cyclin A-CDK2 complexes and a positive regulator of cyclin D-dependent kinases such as CDK4.

P2X3 control peptide for AB5895 and AB5986. Application Antibody blocking (AB5895 and AB5896) Optimal working concentration must be determined by the end user.

Product Source: Expressed in E. coli.

A cell-permeable methylsulfanylimidazole compound that acts as a potent, selective, reversible, and ATP-competitive p38 MAP kinase inhibitor (IC 50 = 0.38 &#181M for p38&#945).

A cell-permeable symmetrical sulfone compound that acts as a potent and ATP-competitive inhibitor of p38&#945/&#946 MAPK (IC 50 = 130 and 550 nM, respectively), while exihibiting much reduced activity (&#880423% inhibition at 1 &#181M) against

A cell-permeable indole compound that acts as a potent, ATP-competitive, and isozyme-selective p38&#945 MAP kinase inhibitor (IC 50 = 3.2 nM).

A cell-permeable pyrazolo-napthalenyl urea compound that acts as a highly potent, slowly binding (IC 50 = 8 and 97 nM, respectively, against human p38&#945, respectively, with or without 2 h preincubation), but high affinity (t 1/2 of dissociation

p38/JTV-1 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex, an essential enzyme that ligates specific amino acids to tRNAs before protein synthesis. It plays a pivotal role in the control of cell

N-terminal GST-tagged, recombinant, human, full-length p38&#945/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose.

N-terminal GST tagged, recombinant, full length p38&#945/SAPK2a Product Source: expressed in E. coli Biochem/physiol Actions Protein Target: p38&#945/SAPK2a Target Sub-Family: CMGC Packaging Also available in 250&#956g size (2x125&#956g) - Call

N-terminal GST tagged, recombinant, full length p38&#945/SAPK2a Product Source: expressed in E. coli Biochem/physiol Actions Protein Target: p38&#945/SAPK2a Target Sub-Family: CMGC Packaging Also available in 250&#956g size (2x125&#956g) - Call