NITISINONE (C005B-313598)

Catalog No.: C005B-313598
Mfr. No.: SML0269-50MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 50
UOM: MG

Price: $847.61

List Price: $941.79

Application Nitisinone has been used: to induce liver injury to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase in supplemented water to block the accumulation of toxic metabolites in human

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Description
Specifications

Application

Nitisinone has been used:

to induce liver injury
to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase
in supplemented water to block the accumulation of toxic metabolites in human hepatocyte engrafted mice
to study its effect on bacterial pyomelanin production

Biochem/physiol Actions

Nitisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase). Nitisinone is used in the treatment of hereditary tyrosinemia type 1, where it blocks the degradation of tyrosine into harmful substances.

UPC:: 51452102
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0269-50MG
CAS:: 104206-65-7

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