General description
Oxalyl chloride is a commonly used chlorinating reagent that can be prepared by the reaction of oxalic acid and phosphorus pentachloride.
Application
Oxalyl chloride may be used in the following processes:
- Preparation of Mosher′s acid chloride by reacting with Mosher′s acid in the presence of DMF.
- Activation of dimethyl sulfoxide for use in the oxidation of long-chain alcohols to carbonyls.
- Activation of α-keto carboxylic acids and N-heterocyclic carboxylic acids for alkynylation to form ynediones and N-heterocyclic ynones, respectively.
Suitable for the synthesis of acid chlorides used to produce liquid crystals.
Reactant involved in:
- Synthesis of N-heterocyclic ynones and ynediones, used to activate carboxylic acids
- Chlorination and halogenation
- Three-component [3+2] cycloadditions
- Reactions with organostannanes
- Synthesis of cyclopentenones
- Carbonylations, used as a carbonyl synthon
Packaging
The 5g, 25g and 100g units sold in the US are packaged in ampules.
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
- UPC:
- 51411615
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 221015-10KG