T16AINH-A01 (C005B-313318)

Catalog No.: C005B-313318
Mfr. No.: SML0493-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $190.33

List Price: $211.47

Application T16Ainh-A01 has been used as an inhibitor of transmembrane protein 16A (TMEM16A). Biochem/physiol Actions T16Ainh-A01 is a selective TMEM16A calcium-activated chloride channel inhibitor that strongly inhibits chloride current in

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Description
Specifications

Application

T16Ainh-A01 has been used as an inhibitor of transmembrane protein 16A (TMEM16A).

Biochem/physiol Actions

T16Ainh-A01 is a selective TMEM16A calcium-activated chloride channel inhibitor that strongly inhibits chloride current in salivary gland cells. T16Ainh-A01 poorly inhibited total CaCC current in intestinal and airway epithelial cells, but blocked mainly an initial, agonist-stimulated transient chloride current. T16Ainh-A01 does not alter cytoplasmic calcium and has little effect on CFTR Cl- conductance.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:: 51162348
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0493-10MG
CAS:: 552309-42-9

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