(+/-)-Bay K8644 (C15-1259-224)

Catalog No.: C15-1259-224
Manufacturer No.: B112-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Price: $2,291.21

List Price: $2,545.79

Application (Â±)-Bay K8644 has been used as an agonist for voltage sensitive calcium channels (VSCCs) in interneurons, L-type calcium channel (LTCC) in human embryonic kidney 293 cells and viscerofugal neurons. Biochem/physiol Actions (Â±)-Bay

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Description
Specifications

Application

(Â±)-Bay K8644 has been used as an agonist for voltage sensitive calcium channels (VSCCs) in interneurons, L-type calcium channel (LTCC) in human embryonic kidney 293 cells and viscerofugal neurons.

Biochem/physiol Actions

(Â±)-Bay K8644 is a 1,4-dihydropyridine (DHP) derivative and an agonist for L-type Ca²⁺ channels. However, it′s enantiomers (-)-BAY k8644 and (+)-BAY k8644 have opposing functionality with respect to Ca2+ channels as high-potency agonist and low-potency antagonist, respectively. (Â±)-Bay K8644 increases influx of Ca²⁺ specifically at voltage-gated calcium channels. It constricts blood vessels and heart contraction.

Increases influx of Ca²⁺ specifically at voltage-gated calcium channels.

UPC:: 41105328
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: B112-25MG

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