General description
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.
Application
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:
- As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.
- Synthesis of structured pure triacylglycerol (TAG) regioisomers.
- As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.
- Synthesis of herceptin- nanoparticles.
Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product.
Legal Information
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51151524
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 12805-25G-F
