(ILE7)-ANGIOTENSIN III ACETATE HYDRATE (C005B-238722)

Biochem/physiol Actions

In [Ile7]-Angiotensin III (Ile7-AIII) the seventh amino acid of angiotensin III (phe) is replaced with isoleucine. [Ile7]-Angiotensin III (Ile7 AIII) is an angiotensin III (A III) receptor antagonist used to selectively block the action of Angiotensin III.

[Ile7]-Angiotensin III is (Ile7-Ang III) used as a peptide angiotensin receptor antagonist often in comparison with other Ang antagonists such as saralasin.

Molecular Weight: 897.08 (anhydrous free base basis). Empirical Formula: C₄₃H₆₈N₁₂O₉ · xC₂H₄O₂ · yH₂O. Quality Level: 200. Assay: ≥. 95% (HPLC). form: powder. color: white. storage temp.: −. 20°C. SMILES string: O.CC(O): O.CC[C@H](C)[C@H](NC(: O)[C@@H]1CCCN1C(: O)[C@H](Cc2c[nH]cn2)NC(: O)[C@@H](NC(: O)[C@H](Cc3ccc(O)cc3)NC(: O)[C@@H](NC(: O)[C@@H](N)CCCNC(N): N)C(C)C)[C@@H](C)CC)C(O): O. InChI: 1S/C43H68N12O9.C2H4O2.H2O/c1-7-24(5)34(40(61)51-31(20-27-21-47-22-49-27)41(62)55-18-10-12-32(55)38(59)54-35(42(63)64)25(6)8-2)53-37(58)30(19-26-13-15-28(56)16-14-26)50-39(60)33(23(3)4)52-36(57)29(44)11-9-17-48-43(45)46. 1-2(3)4. /h13-16,21-25,29-35,56H,7-12,17-20,44H2,1-6H3,(H,47,49)(H,50,60)(H,51,61)(H,52,57)(H,53,58)(H,54,59)(H,63,64)(H4,45,46,48). 1H3,(H,3,4). 1H2/t24-,25-,29-,30-,31-,32-,33-,34-,35-. . /m0../s1. InChI key: YXASJLHKVNKIRW-ZPJCNHGSSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).