General description
An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
Biochem/physiol Actions
Secondary Target
MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively)
Warning
Toxicity: Standard Handling (A)
Other Notes
Ikejiri, M., et al. 2005. J. Biol. Chem.280, 33992.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51144105
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 444286-5MG
- CAS:
- 869577-51-5
