General description
(S)-(-)-Perillic acid is a perillyl derivative with potent antimicrobial and anticancer activity. It can be prepared via bio-oxidation of R-(+)-limonene.
Application
(S)-(−)-Perillic acid (PA) can be used as a starting material for the preparation of:,·
- Aryl amides, 4-(prop-1-en-2-yl)-N-(3-(trifluoromethyl)phenyl)cyclohex-1-ene-1-carboxamide and N-(4-(4-amino-2-methylphenethyl)-3-methylphenyl)-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxamide, as in vitro antiproliferative active agents.
- Machaeriols and cannabinoid-related compounds as antimalarial agents.
- Tricyclic-β-lactone by treating with 1-chloro-N,N-2-trimethylpropenylamine and dimethylketomalonate, followed by addition of 9-azajulolidine.
Biochem/physiol Actions
Interferes with activity of p21ras and other small G proteins by inhibiting post-translational cysteine isoprenylation.
- UPC:
- 51303611
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 218359-1G
- CAS:
- 23635-14-5
