![(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-532)](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/1280x1280/products/860815/688744/cenmed-product-image-placeholder-1-__23782.1717449169.jpg?c=1 "(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-532)")
Application
DSM MonoPhos Family of Highly Efficient Privileged Ligands
Chiral phosphoramidite ligand used in a highly enantioselective copper-catalyzed conjugate addition of diakylzincs to a variety of Michael acceptors. Also used in a palladium-catalyzed diethylzinc mediated umpolung allylation.
The product may be used as a ligand in:
- Iridium-catalyzed allylic etherification of acyclic, achiral allylic carbonates with potassium silanolates to form chiral allylic alcohols.
- Palladium-catalyzed asymmetric allylic cyclisation of N-tosyl and N-benzyl carbonates to form the corresponding pyrrolidine and piperidine derivatives, respectively.
- Intramolecular iridium-catalyzed allylic cyclizationof (E)-allylic methyl carbonates to form 2,5-trans/cis pyrrolidine derivatives.
Features and Benefits
Advantages of the MonoPhos® ligands:
- Superior enantiocontrol in numerous transformations
- High activities at low catalyst loadings
- Hydrogenations under low-pressure conditions
Legal Information
Sold under license from DSM for research purposes only.
MonoPhos is a registered trademark of DSM IP Assets B.V.
- UPC:
- 51293009
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 665290-2G
![(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-533)](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/860816/688745/cenmed-product-image-placeholder-1-__05197.1717449169.jpg?c=1 "(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-533)")
![(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-531)](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/860814/688743/cenmed-product-image-placeholder-1-__07933.1717449169.jpg?c=1 "(s,s,s)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1236-531)")
![(s,r)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-(1-phenylethyl)amine](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/862953/690882/cenmed-product-image-placeholder-1-__03760.1717449930.jpg?c=1 "(s,r)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-(1-phenylethyl)amine")
![(s,r,r)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1243-754)](https://cdn11.bigcommerce.com/s-2u2oi3cvy8/images/stencil/500x659/products/868025/695954/cenmed-product-image-placeholder-1-__92132.1717451683.jpg?c=1 "(s,r,r)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine (c15-1243-754)")
