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(+)-Tubocurarine chloride pentahydrate (C15-1258-678)

Catalog No.
C15-1258-678
Manufacturer No.
93750-250MG
Manufacturer Name
Sigma-Aldrich
Quantity
250
Unit of Measure
MG
Price: $304.29
List Price: $338.10

Application (+)-Tubocurarine chloride pentahydrate has been used: as an acetylcholine receptor antagonist in synapse blocking experiment to study its effect on neuromuscular junction formation (NMJ) formation in a co-culture system of human

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Application

(+)-Tubocurarine chloride pentahydrate has been used:

  • as an acetylcholine receptor antagonist in synapse blocking experiment to study its effect on neuromuscular junction formation (NMJ) formation in a co-culture system of human skeletal muscles and human stem cell-derived motoneurons
  • to induce paralysis in zebrafish larvae to study whole-brain imaging of seizures by two-photon light-sheet microscopy
  • to block NMJ to study its role in myotube contraction

Biochem/physiol Actions

(+)-Tubocurarine chloride pentahydrate serves as a neuromuscular blocker.

Classical competitive antagonist of the nicotinic acetylcholine receptor. Structure-activity relationships and conformational studies for tubocurarine binding at the nicotinic AChR.

UPC:
51152074
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
93750-250MG


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