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(tyr[so3h]27)cholecystokinin fragment 26-33 amide (c15-1225-829)

(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide (C15-1225-829)

Catalog No.
C15-1225-829
Manufacturer No.
C2175-.5MG
Manufacturer Name
Sigma-Aldrich
Quantity
0.5
Unit of Measure
MG
Price: $711.43
List Price: $790.48

Amino Acid Sequence Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 General description (Tyr[SO 3 H] 27 )Cholecystokinin fragment 26-33 amide is a sulfated cholecystokinin(CCK) octapeptide derived from the proCCK. It is present in plasma and endocrine cells.

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Amino Acid Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

General description

(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide is a sulfated cholecystokinin(CCK) octapeptide derived from the proCCK. It is present in plasma and endocrine cells.

Application

(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide has been used to test its effects:

  • to study its effects on β5i/LMP7 immunoproteasome subunit in pancreatitis
  • on gastric emptying,food intake and c-Fos immunoreactivity in small litter (SL) and normal litter (NL) rats
  • on the intestine and gallbladder motility in fish Ballan Wrasse

Biochem/physiol Actions

(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide activates the cholecystokinin type B receptor and may mediate the blockage of opioid analgesia. It elicits anti-inflammatory effects. It mediates the inhibition on cytokine release, lymphocytes, and macrophages.

Neurotransmitter; predominant form of CCK in CNS and gastrointestinal tract; may play a role in satiety.

Other Notes

C-Terminal octapeptide of cholecystokinin

UPC:
51123100
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
C2175-.5MG


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