Amino Acid Sequence
Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
General description
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide is a sulfated cholecystokinin(CCK) octapeptide derived from the proCCK. It is present in plasma and endocrine cells.
Application
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide has been used to test its effects:
- to study its effects on β5i/LMP7 immunoproteasome subunit in pancreatitis
- on gastric emptying,food intake and c-Fos immunoreactivity in small litter (SL) and normal litter (NL) rats
- on the intestine and gallbladder motility in fish Ballan Wrasse
Biochem/physiol Actions
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 amide activates the cholecystokinin type B receptor and may mediate the blockage of opioid analgesia. It elicits anti-inflammatory effects. It mediates the inhibition on cytokine release, lymphocytes, and macrophages.
Neurotransmitter; predominant form of CCK in CNS and gastrointestinal tract; may play a role in satiety.
Other Notes
C-Terminal octapeptide of cholecystokinin
- UPC:
- 51123100
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C2175-1MG