[Tyr(SO3H)63]-Hirudin Fragment 54-65

Sigma-Aldrich

Catalog No.: C15-1203-503
Manufacturer No.: H6894-.1MG
Manufacturer Name: Sigma-Aldrich
Quantity: 0.1
Unit of Measure: MG

Price: $304.90

List Price: $338.78

Amino Acid Sequence Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln Application [Tyr(SO 3 H) 63 ]-hirudin fragment 54-65 has been used to study the effect of thrombin in presence of leupeptin. It is also used to study the effect of hirudin

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Description
Specifications

Amino Acid Sequence

Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln

Application

[Tyr(SO₃H)⁶³]-hirudin fragment 54-65 has been used to study the effect of thrombin in presence of leupeptin. It is also used to study the effect of hirudin peptide on the thrombin-rHCII (recombinant heparin cofactor II)-L444R (leucine 444 to arginine) complex separation.

Biochem/physiol Actions

Hirudin fragment that binds to the regulatory exosite I on thrombin and the regulatory proexosite I on prothrombin. The interaction with thrombin prevents the thrombin-induced activation of clotting factor V. The interaction with prothrombin inhibits the formation of thrombin by factor Xa in the presence of factor Va.

UPC:: 51131610
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: H6894-.1MG

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