General description
1,2-Dibromoethane (DBE) is an organobromine compound that is used as an ‘entrainment reagent′ to activate magnesium in Grignard reagents. It is also a useful reagent for activating zinc. DBE is used as an intermediate in the synthesis of dyes, pesticides and pharmaceuticals.
Application
1,2-Dibromoethane can be used as a reagent to prepare:
- Vinyl bromide and 1,2-disubstituted ethane derivatives.
- Vinyl aromatic compounds by palladium-catalyzed cross-coupling reaction with various arylboronic acids via in situ formation of vinyl bromide.
- 2-arylsulfonyl hydrazones by reacting with aryldiazonium tetrafluoroborates, sulfur dioxide and hydrazines.
It can also be used as a bromine source in organic synthesis to brominate carbanions.
Other Notes
May darken in storage
- UPC:
- 51471503
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 240656-100G