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1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole

1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole

Catalog No.
C15-1226-890
Manufacturer No.
H6036-10MG
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
MG
Price: $475.71
List Price: $528.57

Estrogen receptor α (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor).

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General description

Estrogen receptor α (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole is also termed as PPT. ERα is found in the nuclear and extranuclear sites in principal and inhibitory neurons.

Application

1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole has been used to cultivate differentiated adipocytes. It is also used in drug treatments and radioimmunoassay (RIA).

Biochem/physiol Actions

Estrogen receptor α (ERα) is involved in immune and inflammatory responses. Aberrations in ESR1 results in Mayer-Rokitansky-Kuster-Hauser syndrome that is associated with the congenital absence of the uterus and the upper two-thirds of the vagina.

PPT is a specific estrogen receptor α (ERα) agonist.

UPC:
51293800
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
H6036-10MG


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