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1 4-dioxane acs reagent >=99.0%

1 4-DIOXANE ACS REAGENT >=99.0%

Sigma-Aldrich

Catalog No.
C15-1259-463
Manufacturer No.
676950-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG
Price: $229.29
List Price: $254.76

A Na + channel opener. Increases intracellular Ca 2+ levels without affecting Na + - Ca 2+ exchange.

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General description

A Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+ - Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.

A Na+ channel opener. Increases intracellular Ca2+ levels without affecting Na+-Ca2+ exchange. Acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. Induces cell death in bovine chromaffin cells.

Biochem/physiol Actions

Primary Target
Na+ channel

Warning

Toxicity: Highly Toxic (H)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Maroto, R., et al. 1994. Eur. J. Pharmacol. 270, 331.
Plattner, H., et al. 1994. J. Membr. Biol. 142, 229.
Rando, T.A., et al. 1989. J. Gen. Physiol.93, 43.
Rando, T.A., et al. 1986. Mol. Pharmacol.29, 467.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:
12352103
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
676950-5MG


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