1,8-ANS is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. The emission maximum of 1,8-ANS undergoes a blue shift and fluorescence intensity increases significantly upon binding to low polarity regions of a protein surface. These properties make 1,8-ANS well suited for determining the affinity of hydrophobic ligands to their corresponding binding proteins, such as the binding of free fatty acids to fatty acid binding proteins (FABPs). 1,8-ANS binds to intestinal FABP (FABP2) with a Kd value of ~9.7 µM at 24.5°C.
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- UPC:
- 41106607
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10010219-10000
- CAS:
- 82-76-8
- Model Number:
- C835U78
- Temperature Control Device:
- Yes
