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1-Deoxymannojirimycin hydrochloride (C15-1260-201)

Catalog No.
C15-1260-201
Manufacturer No.
D9160-10MG
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
MG
Price: $1,285.71
List Price: $1,428.57

Chemical structure: glucosamine Application 1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity.

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General description

Chemical structure: glucosamine

Application

1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study it′s effect on allogeneic cytotoxic T lymphocytes (CTL). It is used for studies on Golgi-mediated glycoprotein processing.

Biochem/physiol Actions

1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding.

Selectively inhibits Golgi associated α(1→2) mannosidase and for studies on Golgi-mediated glycoprotein processing.

UPC:
51283003
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
D9160-10MG


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