General description
Chemical structure: glucosamine
Application
1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study it′s effect on allogeneic cytotoxic T lymphocytes (CTL). It is used for studies on Golgi-mediated glycoprotein processing.
Biochem/physiol Actions
1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding.
Selectively inhibits Golgi associated α(1→2) mannosidase and for studies on Golgi-mediated glycoprotein processing.
- UPC:
- 51283003
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D9160-1MG