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1-DEOXYNOJIRIMYCIN HYDROCHLORIDE (C15-1260-104)

Catalog No.
C15-1260-104
Mfr. No.
D9305-5MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
5
UOM
MG
Price: $517.01
List Price: $574.46

Chemical structure: glucosamine Application 1-Deoxynojirimycin hydrochloride has been used to study its effects on the loss-of-function of N-glycosylation pathway on hair cell regeneration as an endoplasmic reticulum (ER) α-glucosidase I

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General description

Chemical structure: glucosamine

Application

1-Deoxynojirimycin hydrochloride has been used

  • to study its effects on the loss-of-function of N-glycosylation pathway on hair cell regeneration
  • as an endoplasmic reticulum (ER) α-glucosidase I and II inhibitor to study its effects on TMED3-cystic fibrosis transmembrane conductance regulator (CFTR) interaction
  • as an insect trehalase inhibitor in TREH inhibition bioassay

Biochem/physiol Actions

1-Deoxynojirimycin (DNJ) is a naturally occurring alkaloid azasugar or iminosugar. It is observed in mulberry leaves, Commelina communis, and bacterial strains including Bacillus and Streptomyces species. DNJ acts as an α-glucosidase inhibitor and exhibits anti-viral anti-diabetic, anti-inflammatory, anti-obesity, and antioxidant properties.

α-Glucosidase inhibitor

UPC:
51102800
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
D9305-5MG
CAS:
73285-50-4

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