1-EBIO (C005B-313878)

Catalog No.: C005B-313878
Mfr. No.: SML0034-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $241.72

List Price: $268.58

Application 1-EBIO was used to study the electrical activity modulated by Ca +2 -activated K + channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied.

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Description
Specifications

Application

1-EBIO was used to study the electrical activity modulated by Ca⁺²-activated K⁺ channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied.

Biochem/physiol Actions

1-EBIO is an activator of epithelial Ca2+-activated K+ channel also known as the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) or KCa3.1.

1-EBIO potentiates the secretion of CFTR-mediated Cl⁻ ion secretion by activating the basolateral KCNN4 K⁺ channels in native human colonic tissues. It stimulates the apical Cl⁻ channels and Ca⁺²-dependent basolateral K⁺ channels to stimulate fluid transport in lacrimal glands.

UPC:: 51171603
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0034-10MG
CAS:: 10045-45-1

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