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1'-hydroxymidazolam (c15-1695-092)

1'-HYDROXMIDAZOLAM (C15-1695-092)

Sigma Aldrich

Catalog No.
C15-1695-092
Manufacturer No.
UC430-10MG
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
MG
Price: $5,016.98
List Price: $5,574.43

General description 1′:-Hydroxymidazolam is the metabolite of midazolam. Application 1′:-Hydroxymidazolam (1′:-OHMDZ) can be used for assessing Cyp3a11 enzyme activity as well as for pharmacokinetic (PK) study of midazolam.

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General description

1′-Hydroxymidazolam is the metabolite of midazolam.

Application

1′-Hydroxymidazolam (1′-OHMDZ) can be used for assessing Cyp3a11 enzyme activity as well as for pharmacokinetic (PK) study of midazolam.

CYP3A4 metabolite of midazolam.

Biochem/physiol Actions

1′-Hydroxymidazolam is the major hydroxylated metabolite of Midazolam (MDZ), forms due to rapid and extensive metabolization of MDZ by the CYP 450 3A isoenzymes in the liver. The product contributes to the pharmacological impact of MDZ.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

UPC:
51452401
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
UC430-10MG
Product Size:
10/MG
CAS:
59468-90-5

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