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10058-f4 (c15-1237-918)

10058-F4 (C15-1237-918)

Catalog No.
C15-1237-918
Manufacturer No.
F3680-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG
Price: $184.29
List Price: $204.76

Application 10058-F4 has been used: as c-Myc inhibitor to treat stromal cells as c-Myc inhibitor to determine the effect of c-Myc inhibition on cardiac progenitor cells (CPC) growth as c-Myc inhibitor to culture T cells to treat C4-2 cells to

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Application

10058-F4 has been used:

  • as c-Myc inhibitor to treat stromal cells
  • as c-Myc inhibitor to determine the effect of c-Myc inhibition on cardiac progenitor cells (CPC) growth
  • as c-Myc inhibitor to culture T cells
  • to treat C4-2 cells to examine the activity of MST1 promoter luciferase reporter construct

Biochem/physiol Actions

10058-F4 is a c-Myc inhibitor that induces cell-cycle arrest and apoptosis. 10058-F4 is a cell-permeable thiazolidinone that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. 10058-F4 inhibits tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

UPC:
51442705
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
F3680-5MG


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