Contains four deuterium atoms at the 3, 3', 4, and 4' positions. Intended for use as an internal standard for the quantification of 11β-PGF2α by GC- or LC-mass spectrometry. The primary plasma metabolite of PGD2 in vivo. Normal human urinary excretion of 11β-PGF2α is about 54 ng/mmol creatinine, which is increased nearly 3-fold during allergen-induced bronchoconstriction in asthmatics. It is equipotent to PGF2α in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation. 11β-PGF2α inhibits ADP or thrombin-induced human platelet aggregation at concentrations of 0.14 to 2.8 μM. Specification: A solution in ethanol Molecular Formula: C20H30D4O5 Molecular Weight: 358.5 PubChem CID: 156593932
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P345613-100μg
- CAS:
- 1240398-18-8
- Product Size:
- 100μg
