11-trans Leukotriene C4-25 ÃƒÆ’Ã†â¦g

Catalog No.: C003B-379657
Mfr. No.: 20230-25
Mfr. Name: Cayman Chemical Company
Qty/UOM: 1
UOM: EA

Price: $405.89

List Price: $450.99

11-trans LTC4 is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage.

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Description
Specifications

11-trans LTC4 is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum as a cysteinyl leukotriene receptor preparation, the pKis for LTC4 and 11-trans LTC4 were determined to be 6.42 and 6.58, respectively.

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UPC:: 51182430
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: Yes
WeightUOM:: LB
MPN:: 20230-25

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