13,14-dihydro-15-keto Prostaglandin E2

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 biosynthesized by the enzymes 15-hydroxy PGDH and 15-oxo-PG δ13-reductase. This compound accumulates to detectable levels, and then undergoes further metabolism and chemical decomposition, giving it a relatively short half-life (~ 9 minutes), but that is longer than PGE2 (~ 2 minutes), allowing this compound to build up to appreciable levels during PGE2 expression. Receptor binding studies indicate that although metabolites of prostaglandins typically bind to EP receptors with lower affinity, they might still play an important role in these biochemical pathways. Specifications and Purity: 95%，10mg/ml in methyl acetate. Molecular Formula: C20H32O5. Molecular Weight: 352.50. PubChem CID: 5280711. Isomeric SMILES: CCCCCC(=O)CC[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C/CCCC(=O)O)O. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D356081-SCI_aeab37d6f413f7277ae323f622c75083.pdf.