EDHF (endothelium-derived hyperpolarizing factor), an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin, is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. CYP450 metabolism of polyunsaturated fatty acids produces epoxides such as 14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been little studied relative to arachidonate epoxygenase metabolites. 14(15)-EpETE is the ω-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of 14(15)-EpETE has not yet been determined. Specification: A solution in ethanol Molecular Formula: C20H30O3 Molecular Weight: 318.5 PubChem CID: 71433622 Isomeric SMILES: CCC=CC[C@@H]1[C@@H](O1)CC=CCC=CCC=CCCCC(=O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/E343079-SCI_ca8255c7e7e1b99a8120c686a42be4f1.pdf
- UPC:
- 12352211
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- E343079-100μg
- CAS:
- 131339-24-7
- Product Size:
- 100μg
- Hazard Statement Codes:
- H225:H350
- Precautionary Statement Codes:
- P201:P210:P202:P233:P240:P242:P243:P281
