15-deoxy-Δ|12,14|-Prostaglandin J|2|is one of the cyclopentenone PGs, which have documented metabolic (peroxisome proliferator-activated receptor γ-activating), antimitotic, and antiproliferative effects.(1,2,3) The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical pathways. An affinity probe that allows 15-deoxy-Δ|12,14|-PGJ|2|to be detected through an interaction with the biotin ligand. 15-deoxy-Δ|12,14|-PGJ|2|-biotinamide was designed to allow 15-deoxy-Δ|12,14|-PGJ|2|to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.15-deoxy-Δ12,14-Prostaglandin J2-biotinamideis a cyclopentenone PG with metabolic, antimitotic, and antiproliferative effects. Specification: A solution in ethanol Molecular Formula: C35H54N4O4S Molecular Weight: 626.9 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D393063-SCI_9cdf80693f48be2cd4dcd1d02eef776a.pdf
- UPC:
- 12352111
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D393063-50μg
- Product Size:
- 50μg
- Hazard Statement Codes:
- H225:H333:H350
- Precautionary Statement Codes:
- P201:P210:P202:P233:P240:P242:P243:P281
