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16(17)-epdpe (c09-0880-059)

16(17)-EpDPE (C09-0880-059)

Aladdin

Catalog No.
C09-0880-059
Manufacturer No.
E384695-50μg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $134.82
List Price: $149.81

EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin)

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EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as 14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been little studied relative to arachidonate epoxygenase metabolites. 16(17)-EpDPE is the DHA homolog of 14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of docosahexaenoic acid (DHA). The EDHF activity of 16(17)-EpDPE has not yet been determined and the epoxygenase metabolites of DHA have also been detected in a murine inflammation model.16(17)-EpDPEis the DHA homolog of 14(15)-EpETrE, significant to CYP450 metabolism. Specifications and Purity: A solution in ethanol. Molecular Formula: C22H32O3. Molecular Weight: 344.5. PubChem CID: 35020781. Isomeric SMILES: CC/C=C\C[C@@H]1[C@@H](O1)C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O.
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
0.96 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
E384695-50μg
Product Size:
50μg


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