Electrolyte and fluid transport in the kidney are regulated partially by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, and does not affect perfusion pressure. At a concentration of 2 μM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, while the (R)-isomer has negligible effects on ATPase activity. Specification: A solution in ethanol Molecular Formula: C20H32O3 Molecular Weight: 320.46 PubChem CID: 6442739 Isomeric SMILES: CCCCC(/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/H345913-SCI_ee830e73d11d5c13604470760d9f86b9.pdf
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- H345913-50μg
- CAS:
- 128914-46-5
- Physical Hazards:
- Flammable Liquid
- Product Size:
- 50μg
- Hazard Statement Codes:
- H225:H350
- Precautionary Statement Codes:
- P201:P210:P202:P233:P240:P242:P243:P281
