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1alpha-hydroxyvitamin d3

1alpha-Hydroxyvitamin D3

Catalog No.
C15-1238-315
Manufacturer No.
17946-1MG
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
MG
Price: $912.00
List Price: $1,013.33

1α-Hydroxyvitamin D 3 , also known as alfacalcidol, is a synthetic vitamin D 3 analogue, hydroxylated in position one. It is metabolized to 1,25-dihydroxycholecalciferol by 25-hydroxylases.

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General description

1α-Hydroxyvitamin D3, also known as alfacalcidol, is a synthetic vitamin D3 analogue, hydroxylated in position one. It is metabolized to 1,25-dihydroxycholecalciferol by 25-hydroxylases.

Biochem/physiol Actions

1α-Hydroxyvitamin D3 facilitates calcium absorption and deposition. It also has an ability to inhibit bone resorption and stimulate bone formation. Alfacalcidol is used for treating various bone diseases such as rickets/osteomalacia, renal osteodystrophy and osteoporosis. It acts as a chemopreventive agent and reduces the risk colitis and carcinogenesis.

Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

UPC:
51192431
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
17946-1MG


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