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2-(14,15-epoxyeicosatrienoyl) glycerol (c09-0878-381)

2-(14,15-Epoxyeicosatrienoyl) Glycerol (C09-0878-381)

Aladdin

Catalog No.
C09-0878-381
Manufacturer No.
E341170-50μg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $830.28
List Price: $922.53

2-(14,15-Epoxyeicosatrienoyl) Glycerol (2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. 2-14,15-EG is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells at concentrations

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2-(14,15-Epoxyeicosatrienoyl) Glycerol (2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. 2-14,15-EG is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells at concentrations as low as 100 nM and doubling cell proliferation rates at 1 μM. In these cells, 2-14,15-EG activates the metalloprotease ADAM17 (TACE), which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway. Specification: A solution in acetonitrile,≥95% Molecular Formula: C23H38O5 Molecular Weight: 394.54 PubChem CID: 53481916 Isomeric SMILES: CCCCCC1C(O1)C/C=C/C/C=C/C/C=C/CCCC(=O)OC(CO)CO Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/E341170-SCI_ee3b2257ed8ccd731010f2bf5a902f57.pdf
UPC:
12352211
Condition:
New
Availability:
8-12 weeks
Weight:
0.96 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
E341170-50μg
CAS:
848667-56-1
Product Size:
50μg
Hazard Statement Codes:
H225:H319:H302+H312+H332
Precautionary Statement Codes:
P210:P233:P240:P242:P243:P261:P264:P270:P271:P280


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