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2 2-DIMETHYL-1 3-DIOXANE-4 6-DIONE 98% (C15-1222-196)

Catalog No.
C15-1222-196
Mfr. No.
210145-25G
Mfr. Name
Sigma-Aldrich
Qty/UOM
25
UOM
GR
Price: $132.04
List Price: $146.72

2,2-Dimethyl-1,3-dioxane-4,6-dione (Meldrum′s acid) is widely used in organic synthesis, especially for multiple C-C bond formations due to its adequate acidity (p K a 4.83) and steric rigidity .

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General description

2,2-Dimethyl-1,3-dioxane-4,6-dione (Meldrum′s acid) is widely used in organic synthesis, especially for multiple C-C bond formations due to its adequate acidity (pKa 4.83) and steric rigidity. Knoevenagel condensation reaction between aldehydes and Meldrum′s acid are accelerated in ionic liquids.

Meldrum′s acid is used as a valuable starting material to synthesize heterocycles and as intermediates in organic synthesis reactions.

Application

2,2-Dimethyl-1,3-dioxane-4,6-dione was used in the synthesis of:

  • macrocyclic β-keto lactone
  • 4-pyridyl-substituted heterocycles
  • 2-substituted indoles
  • isofraxidin.

UPC:
12352200
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
210145-25G
CAS:
2033-24-1

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