2,4-Dichloro-5-fluoropyrimidine (C09-0833-052)

Application：2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors. Specifications and Purity: 98%. MDL Number: MFCD00233551. Molecular Formula: C4HCl2FN2. Molecular Weight: 166.97. PubChem CID: 250705. Isomeric SMILES: C1=C(C(=NC(=N1)Cl)Cl)F. Beilstein Registry Number: 23(5)5,346. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D119251-SCI_d1b3f4b3d04822dd6589894706311c84.pdf.