General description
2,6-Di-tert-butyl-4-methylpyridine is a sterically hindered, non-nucleophilic base which distinguishes between BrÖnsted (protonic) and Lewis acids. It also enables the direct high-yield conversion of aldehydes and ketones to vinyl triflates. It inhibits desilylation and hydration of the products during GaCl3-catalyzed ortho-ethynylation of phenol.
Application
2,6-Di-tert-butyl-4-methylpyridine has been used:
- in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives
- as base in PtCl4-catalyzed cyclization reactions of homopropargyl azide derivatives
- diastereoselective synthesis of β-thiomannopyranosides
- UPC:
- 51283954
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 249505-5G