2-Dicyclohexylphosphino-2′,6′-diisopropoxybiphenyl (C09-0832-742)

ligand for Arylations Buchwald-Hartwig Cross Coupling Reaction Negishi Coupling Sonogashira Coupling Suzuki-Miyaura CouplingBulky phosphine ligand used in a palladium-catalyzed cross-coupling of aminoethyltrifluoroborates with electron-poor aryl bromides.ApplicationFinds application in Buchwald-Hartwig cross coupling reactions, Arylation, Negishi and Sonogashira coupling reactions. A Ruphos-mediated Suzuki cross-coupling between (hetero)aryl bromides and secondary alkyltrifluoroborates is described using palladium catalysis. The Ruphos ligand showed superior properties as compared to S-Phos in this type of reaction. This method constitutes a valuable extension to current methods for the straightforward production of secondary-alkylated (hetero)aryl derivatives. Specification: 0.98 MDL Number: MFCD06798294 Molecular Formula: C30H43O2P Molecular Weight: 466.64 PubChem CID: 16217985 Isomeric SMILES: CC(C)OC1=C(C(=CC=C1)OC(C)C)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D115625-SCI_73720528cd05269111d8432e8b5b94bf.pdf