2-FLUORO-5-NITROBENZOIC ACID 98%

Catalog No.: C005B-059088
Mfr. No.: 362654-5G
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: GR

Price: $80.09

List Price: $88.99

2-Fluoro-5-nitrobenzoic acid is reported to react with an aldehyde, isonitrile and a primary amine tethered to a Boc-protected internal amino or hydroxyl nucleophile, to afford the Ugi product. Application 2-Fluoro-5-nitrobenzoic acid may be used

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Description
Specifications

General description

2-Fluoro-5-nitrobenzoic acid is reported to react with an aldehyde, isonitrile and a primary amine tethered to a Boc-protected internal amino or hydroxyl nucleophile, to afford the Ugi product.

Application

2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of:

dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (S_NAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support
synthesis of substituted dibenzazocines on solid support, via S_NAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols
in the synthesis of oxazepines

UPC:: 51472700
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: 362654-5G
CAS:: 7304-32-7

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