IRF1-IN-2 (Compound I-19) is an IRF1 inhibitor. IRF1-IN-2 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-2 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1 , GSDMD , IL-1 and PARP1 ; inhibits the Pho of TKB1, upregulates GPX4 and downregulates FACL4). IRF1-IN-2 has a protective effect on ionizing radiation-induced inflammatory skin injury .
Specification: ≥99%
Molecular Formula: C18H20N2O4S
Molecular Weight: 360.400
PubChem CID: 1090685
- UPC:
- 51284907
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M945581-25mg
- Product Size:
- 25mg
- CAS:
- 708245-32-3